In 1996, the South Carolina Office on Aging provided a grant for the construction of senior centers. Locally, the Trident Area Agency on Aging assumed the task of finding a sponsor to shepherd the process. The City of Charleston requested input from its senior population on their needs and desires for such a center. Out of initial discussions, a group of about 25 volunteers organized themselves into the Lowcountry Senior Coalition, a nonprofit group set up to raise additional funds needed to build the center, as well as to provide the city with input and advice. Today, this coalition continues its support as Friends of the Lowcountry Senior Center, a 501(c)3 organization.
In 1998, Roper St. Francis Healthcare became involved when the City of Charleston sought a manager for the project. Charleston County aided as a financial partner, and a strong alliance was formed. In May of 2002, the Lowcountry Senior Center opened its doors to the public, serving independent senior adults aged 50 and older. Currently there are more than 1,400 members, and an average of 250 members and visitors are served each day.
In 2005, the center was honored with two special distinctions: the NuStep Pinnacle Award – a national award for excellence in wellness programming for seniors; and in April 2005, the center became the first in South Carolina to achieve national accreditation by the National Institute of Senior Centers (NISC). This five-year accreditation represents official recognition that the Lowcountry Senior Center is meeting its mission in a nationally accepted and professional manner. Accreditation was achieved once again in 2010.